ChemicalBook > CAS DataBase List > LAPAQUISTAT
LAPAQUISTAT
- Product Name
- LAPAQUISTAT
- CAS No.
- 189060-13-7
- Chemical Name
- LAPAQUISTAT
- Synonyms
- TAK-475;CS-1400;LAPAQUISTAT;Lapaquistat Acetate;Lapaquistat Acetate (TAK-475);Lapaquistat and Lapaquistat Acetate;1-[[(3R,5S)-1-[3-(Acetyloxy)-2,2-dimethylpropyl]-7-chloro-5-(2,3-dimethoxyphenyl)-1,2,3,5-tetrahydro-2-oxo-4,1-benzoxazepin-3-yl]acetyl]-4-piperidineacetic acid;2-[1-[2-[1-(3-Acetoxy-2,2-diMethylpropyl)-7-chloro-5(S)-(2,3-diMethoxyphenyl)-2-oxo-1,2,3,5-tetrahydro-4,1-benzoxazepin-3(R)-yl]acetyl]piperidin-4-yl]acetic acid;4-Piperidineacetic acid, 1-[2-[(3R,5S)-1-[3-(acetyloxy)-2,2-dimethylpropyl]-7-chloro-5-(2,3-dimethoxyphenyl)-1,2,3,5-tetrahydro-2-oxo-4,1-benzoxazepin-3-yl]acetyl]-;2-(1-(2-((3R,5S)-1-(3-Acetoxy-2,2-dimethylpropyl)-7-chloro-5-(2,3-dimethoxyphenyl)-2-oxo-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-3-yl)acetyl)piperidin-4-yl)acetic acid
- CBNumber
- CB01509119
- Molecular Formula
- C33H41ClN2O9
- Formula Weight
- 645.14
- MOL File
- 189060-13-7.mol
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LAPAQUISTAT Property
- Melting point:
- 194-196℃
- Boiling point:
- 826.4±65.0 °C(Predicted)
- Density
- 1.246±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 4.66±0.10(Predicted)
- color
- White
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML2168
- Product name
- TAK-475
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $155
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML2168
- Product name
- TAK-475
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $603
- Updated
- 2024/03/01
TRC
- Product number
- L175500
- Product name
- LapaquistatAcetate
- Packaging
- 25mg
- Price
- $10725
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0007318
- Product name
- LAPAQUISTAT ACETATE
- Purity
- 95.00%
- Packaging
- 25MG
- Price
- $12370.05
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0007318
- Product name
- LAPAQUISTAT ACETATE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $7230.3
- Updated
- 2021/12/16
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LAPAQUISTAT Chemical Properties,Usage,Production
Uses
A novel squalene synthase inhibitor. Lapaquistat acetate decreased plasma cholesterol and triglyceride levels, by lowering lipoproteins containing apoB100. Treatment with Lapaquistat acetate increased collagen concentration and transformed coronary plaques into fibromuscular plaques. Lapaquistat acetate also suppressed the expression of matrix metalloproteinase-1 and plasminogen activator inhibitor-1 in the plaque and increased peripheral coenzyme Q10 levels.Antiarteriosclerotics.
LAPAQUISTAT Preparation Products And Raw materials
Raw materials
Preparation Products
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LAPAQUISTAT Suppliers
- Tel
- 1-(800)-881-8210
- Fax
- 615-250-9817
- inquiries@lgmpharma.com
- Country
- United States
- ProdList
- 2127
- Advantage
- 70
- Tel
- +1-5166625404
- Fax
- 1-516-927-0118
- Info@alfa-chemistry.com
- Country
- United States
- ProdList
- 21317
- Advantage
- 58
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19892
- Advantage
- 58
- Tel
- +1 (732)236-3202
- sales@cckinase.com
- Country
- United States
- ProdList
- 2738
- Advantage
- 58
- Tel
- 16314854226
- info@bocsci.com
- Country
- United States
- ProdList
- 9926
- Advantage
- 65
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